Is melphalan a brand name?
Megace Alkeran is the trade name for melphalan. L-PAM and L-Sarcolysin and phenylalanine mustard are other names for melphalan. In some cases, health care professionals may use the trade name megace alkeran or other names L-PAM or L-Sarcolysin or phenylalanine mustard when referring to the generic drug name melphalan.
Is melphalan expensive?
This is a brand name drug and a generic may be available. The average cost for 50 Tablet(s), 2mg each of the generic (melphalan) is $610.99. You can buy melphalan at the discounted price of $89.99 by using the WebMDRx coupon, a savings of 85%.
Who makes melphalan?
STOCKHOLM — February 26, 2021 — Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO), a global biotech company focused on the development of therapies for difficult-to-treat hematological diseases, today announced that the U.S. Food and Drug Administration, FDA, has approved PEPAXTO® (melphalan flufenamide, also known as …
What class of drug is melphalan?
Melphalan is in a class of medications called alkylating agents. It works by stopping or slowing the growth of cancer cells in your body.
Is melphalan hydrophobic?
Melphalan is hydrophilic and its intracellular accumulation correlates with peptidase expression/activity.
Is melphalan an alkylating agent?
Melphalan is an antineoplastic agent that acts as a bifunctional alkylating agent. It is used in the treatment of multiple myeloma, advanced ovarian adenocarcinoma, early and advanced breast cancer, childhood neuroblastoma, and polycythaemia vera.
What is the cost for melphalan?
MELPHALAN is a chemotherapy drug. This medicine is used to treat multiple myeloma and ovarian cancer. The lowest GoodRx price for the most common version of melphalan is around $149.44, 76% off the average retail price of $625.16.
What is melphalan used to treat?
Melphalan injection is used to treat multiple myeloma (bone marrow cancer) before receiving a stem cell transplant (conditioning treatment). Melphalan belongs to the group of medicines called alkylating agents (cancer medicines).
Does melphalan cause hair loss?
Thinning or loss of your hair will usually start within two to four weeks of your first dose of melphalan. You may also have thinning or loss of eyelashes, eyebrows and other body hair.
Is melphalan toxic?
* Breathing Melphalan can irritate the nose, throat and lungs. * Exposure to Melphalan can damage the bone marrow causing reduced red blood cell (anemia) and white blood cell counts (reduced resistance to infections), and/or reduced platelets (bruising and bleeding). * Melphalan may damage the liver and kidneys.
Is melphalan a chemotherapy?
Melphalan is a chemotherapy treatment for a number of different cancers types. You might also have it before a stem cell or bone marrow transplant. It is also known as Alkeran.
How long does it take for melphalan hair to grow back?
They will typically grow back after several weeks and up to two months. Some patients report that they lose their eyelashes and/or eyebrows more than once before they stay for good. This is normal. Eyebrows, if you do lose them, are the last to go and can occur even a few months after your last dose of chemo.
What is another name for melphalan?
L-PAM and L-Sarcolysin and phenylalanine mustard are other names for melphalan. In some cases, health care professionals may use the trade name megace alkeran or other names L-PAM or L-Sarcolysin or phenylalanine mustard when referring to the generic drug name melphalan.
Where can I find FDA label information for melphalan?
FDA label information for this drug is available at DailyMed. Melphalan is approved for palliative treatment of: Multiple myeloma. Ovarian epithelial cancer that cannot be removed by surgery. Melphalan is also being studied in the treatment of other types of cancer.
What is melfalán used for?
El melfalán se usa para tratar el mieloma múltiple (un tipo de cáncer de la médula ósea). El melfalán también se usa para tratar un tipo determinado de cáncer de ovario (cáncer que empieza en los órganos reproductores femeninos donde se forman los óvulos). El melfalán pertenece a una clase de medicamentos denominados agentes alquilantes.
What does melphalan look like?
Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells. Melphalan appears as white to buff-colored powder. Odorless or with a faint odor.